Analyzer and method for aspirating specimen

ABSTRACT

An analyzer comprising: a specimen container setting portion including a plurality of container holders for holding a plurality of specimen containers of different types; an aspiration section for aspirating the specimen from the specimen container set in the specimen container setting portion; a sensor for detecting the presence of the specimen container set in at least one of the plurality of container holders; and a controller for determining in which of the plurality of container holders the specimen container is set based on the detection result of the sensor, and controlling the operation of the aspiration section, is disclosed. A method for aspirating a specimen is also disclosed.

RELATED APPLICATIONS

This application claims priority under 35 U.S.C. §119 to Japanese Patent Application No. JP2008-169906 filed Jun. 30, 2008, the entire content of which is hereby incorporated by reference.

FIELD OF THE INVENTION

The present invention relates to analyzers and methods for aspirating specimens, in particular, to an analyzer including a specimen container setting portion capable of holding a plurality of specimen containers of different types, and a method for aspirating the specimen by the analyzer.

BACKGROUND

An analyzer including a specimen container setting portion capable of holding a plurality of specimen containers of different types is known (see e.g., Japanese Laid-Open Patent Publication No. 11-295321).

Japanese Laid-Open Patent Publication No. 11-295321 discloses a specimen examining device including a specimen container holder with a plurality of insertion holes of different inner diameters for holding the specimen container, and a sampling nozzle, wherein the specimen container holder can rotate with a predetermined axis positioned at substantially the center of the plurality of insertion holes as the center of rotation. The specimen examining device is configured such that when setting the specimen container in the specimen container holder, the user can set the specimen container after manually rotating the specimen container holder to arrange the insertion hole depending on the type of specimen container at a predetermined position. The sampling nozzle is moved to the position where the specimen container is set, and the specimen accommodated in the set specimen container is aspirated. The plurality of specimen containers of different types then can be responded.

While the plurality of specimen containers of different types can be responded in the specimen examining device described in Japanese Laid-Open Patent Publication No. 11-295321, the user needs to manually rotate the specimen container holder when setting the specimen container, which is a burden on the user.

SUMMARY OF THE INVENTION

The scope of the present invention is defined solely by the appended claims, and is not affected to any degree by the statements within this summary.

A first aspect of the present invention is an analyzer comprising: a specimen container setting portion including a plurality of container holders for holding a plurality of specimen containers of different types; an aspiration section for aspirating the specimen from the specimen container set in the specimen container setting portion; a sensor for detecting the presence of the specimen container set in at least one of the plurality of container holders; and a controller for determining in which of the plurality of container holders the specimen container is set based on the detection result of the sensor, and controlling the operation of the aspiration section.

A second aspect of the present invention is an analyzer comprising: a specimen container setting portion including a plurality of container holders for holding a plurality of specimen containers of different types; an aspiration section for aspirating the specimen from the specimen container set in the specimen container setting portion; a moving assembly for moving the specimen container setting portion to a specimen set position at which the specimen container is set and an aspiration position at which the specimen is aspirated by the aspiration section; a sensor for detecting the presence of the specimen container set in at least one of the plurality of container holders; and a controller for controlling the operation of the moving assembly so that the specimen container set in one of the plurality of container holders is moved to the aspiration position based on the detection result of the sensor.

A third aspect of the present invention is a method for aspirating a specimen comprising: receiving a specimen container in one of a plurality of container holders for holding a plurality of specimen containers of different types; moving a predetermined container holder of the plurality of container holders to a detection position by a sensor for detecting the presence of the specimen container; detecting the presence of the specimen container by the sensor; determining a movement distance of the container holder the received specimen container moves to an aspiration position of the specimen by an aspiration section based on the detection result of the sensor; moving the container holder according to the determined movement distance; and aspirating the specimen from the specimen container by the aspiration section.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 is a perspective view showing an overall configuration of a blood analyzer according to one embodiment of the present invention;

FIG. 2 is a perspective view describing details of each unit of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 3 is a schematic view showing a measurement unit and a specimen conveying device of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 4 is a perspective view showing the measurement unit and the specimen conveying device of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 5 is a perspective view showing a rack and a long vial of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 6 is a perspective view showing a microtube of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 7 is a perspective view showing the vicinity of a specimen aspiration section of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 8 is a perspective view showing a specimen setting portion of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 9 is a perspective view showing the vicinity of a sample container transfer section and a fixing holder of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 10 is a view describing the position of the movement portion of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 11 is a perspective view showing the vicinity of a fixing holder of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 12 is a perspective view showing the vicinity of the fixing holder of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 13 is view describing a configuration of the fixing holder of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 14 is view describing the configuration of the fixing holder of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 15 is a plan view describing a specimen conveying device of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 16 is a side view describing the specimen conveying device of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 17 is a side view describing the specimen conveying device of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 18 is a block diagram describing a control device of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 19 is a view showing a priority specimen measurement instruction screen of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 20 is a flowchart describing a measurement processing operation by the measurement process program of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 21 is a flowchart describing the operation in the priority specimen measurement of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 22 is a state diagram describing the operation in the priority specimen measurement of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 23 is a state diagram describing the operation in the priority specimen measurement of the blood analyzer according to one embodiment shown in FIG. 1;

FIG. 24 is a state diagram describing the operation in the priority specimen measurement of the blood analyzer according to one embodiment shown in FIG. 1; and

FIG. 25 is a state diagram describing the operation in the priority specimen measurement of the blood analyzer according to one embodiment shown in FIG. 1.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

The preferred embodiments of the present invention will be described hereinafter with reference to the drawings.

FIG. 1 is a perspective view showing an overall configuration of a blood analyzer according to one embodiment of the present invention. FIGS. 2 to 19 are views describing the details of each unit of the blood analyzer according to one embodiment shown in FIG. 1. First, the overall configuration of the blood analyzer 1 according to one embodiment of the present invention will be described with reference to FIGS. 1 to 19. In the present embodiment, a case in which the present invention is applied to the blood analyzer serving as one example of the analyzer will be described.

In the present embodiment, as shown in FIGS. 5 and 6, a sample container 100 for accommodating blood, which is a specimen, includes a long vial 101 (see FIG. 5), which is a specimen container of a vertically long shape, having a rubber sealing lid 101 a, and a microtube 102 (see FIG. 6), which is a specimen container for mainly accommodating a small amount of specimen, smaller than the long vial 101. In the description of the present embodiment, description is made using “sample container 100” to include both the long vial 101 and the microtube 102 when corresponding to both the long vial 101 and the microtube 102, and description is made using the “long vial 101” or the “microtube 102” when corresponding to only one of the long vial 101 or the microtube 102.

As shown in FIGS. 1 and 2, the blood analyzer 1 according to the present embodiment includes two measurement units, first measurement unit 2 and second measurement unit 3, a specimen conveying device (sampler) 4 arranged on the front surface side (side on direction of arrow Y1) of the first measurement unit 2 and the second measurement unit 3, and a control device 5 including a PC (personal computer) electrically connected to the first measurement unit 2, the second measurement unit 3, and the specimen conveying device 4. The blood analyzer 1 is connected to a host computer 6 (see FIG. 3) by the control device 5.

As shown in FIGS. 1 to 4, the first measurement unit 2 and the second measurement unit 3 are measurement units of substantially the same type, and are arranged adjacent to each other. Specifically, in the present embodiment, the second measurement unit 3 measures the specimen for the same measurement item by using the same measurement principle as the first measurement unit 2. Furthermore, the second measurement unit 3 performs measurement on the measurement item that is not analyzed by the first measurement unit 2. As shown in FIG. 3, the first measurement unit 2 and the second measurement unit 3 respectively include specimen aspiration sections 21, 31 for aspirating the blood, which is the specimen, from a sample container (test tube) 100, sample preparation sections 22, 32 for preparing the detection sample from the blood aspirated by the specimen aspiration sections 21, 31, and detection sections 23, 33 for detecting the blood cells of the blood from the detection sample prepared by the sample preparation sections 22, 32.

Each of the first measurement unit 2 and the second measurement unit 3 also includes unit covers 24, 34 for interiorly accommodating the specimen aspiration sections 21, 31 and the sample preparation sections 22, 32; sample container conveying sections 25, 35 for retrieving the sample container 100 inside the unit covers 24, 34 and conveying the sample container 100 to aspiration positions 600, 700 (see FIG. 3) by the specimen aspiration sections 21, 31; presence detection sections 26, 36 for detecting the presence of the long vial 101 conveyed to the inside by the sample container conveying sections 25, 35; and fixing holders 27, 37 for fixedly holding the long vial 101 at the aspiration positions 600 and 700 (see FIG. 3). As shown in FIGS. 1 and 2, on the outer surface of front surface portions 241, 341 of the unit covers 24, 34, specimen setting portion open/close buttons 28, 38, priority specimen measurement start buttons 29, 39, and openings 241 a, 341 a through which movement portions 255 d, 355 d, to be hereinafter described, of the sample container conveying sections 25, 35 pass are respectively arranged.

As shown in FIG. 7, the specimen aspiration sections 21 and 31 include pipettes 211 and 311, and pipette movement portions 212, 312, respectively. The pipettes 211 and 311 have the distal ends formed such that the sealing lid 101 a (see FIG. 5), to be hereinafter described, of the long vial 101 can be passed through. The pipette movement portions 212 and 312 have a function of moving the pipettes 211 and 311 in a vertical direction (direction of arrows Z1 and Z2), respectively. The pipette movement portions 212 and 312 have horizontal arms 213, 313 for fixedly holding the pipettes 211, 311, screw shafts 214, 314 passing through the horizontal arms 213, 313 in the vertical direction (direction of arrows Z1 and Z2), and nuts 215, 315 to be screwed to the screw shafts 214, 314, respectively. Furthermore, the pipette movement portions 212 and 312 each has slide rails 216, 316 arranged parallel (direction of arrows Z1 and Z2) to the screw shafts 214, 314, slidable members 217, 317 slidably attached to the slide rails 216, 316, and stepping motors 218, 318. The horizontal arms 213, 313 are fixed to the nuts 215, 315 and the slidable members 217, 317, respectively.

Pulleys 214 a, 314 a are attached to the upper ends of the screw shafts 214, 314, respectively. Pulleys 218 a, 318 a are attached to output shafts of the stepping motors 218, 318, respectively. Annularly formed timing belts 219, 319 are turnably stretched between the pulleys 214 a, 314 a and the pulleys 218 a, 318 a. The rotational drive of the stepping motor 218 (318) is transmitted to the screw shaft 214 (314) via the timing belt 219 (319) to thereby rotate the screw shaft 214 (314), so that the horizontal arm 213 (313) moves in the vertical direction (direction of arrows Z1 and Z2). The pipette 211 (311) is moved in the vertical direction (direction of arrows Z1 and Z2) with the movement in the vertical direction (direction of arrows Z1 and Z2) of the horizontal arm 213 (313).

The stepping motor 218 (318) is configured to be able to fluctuate the rotary torque according to the supplied current value (magnitude of drive pulse). The stepping motor 218 (318) is configured to lose synchronism when a load of greater than or equal to the rotary torque of the motor is applied. Specifically, the stepping motor 218 (318) is controlled such that the rotary torque becomes small when aspirating the blood accommodated in the microtube 102 (see FIG. 6) compared to when aspirating the blood accommodated in the long vial 101 (see FIG. 5), and is configured to lose synchronism when the distal end of the pipette 211 (311) contacts the bottom portion of the microtube 102. Thus, the microtube 102 can be prevented from being damaged even if the distal end of the pipette 211 (311) contacts the bottom portion of the microtube 102. The specimen accommodated in the microtube 102 of small accommodation capacity can be aspirated barely without waste by the specimen aspiration section 21 (31) by causing the distal end of the pipette 211 (311) to reach the bottom portion of the microtube 102.

When aspirating the blood accommodated in the long vial 101 of larger accommodation capacity than the microtube 102, the stepping motor 218 (318) is controlled to lower the pipette 211 (311) at a predetermined rotary torque, and after the pipette 211 (311) passes through the sealing lid 101 a, to lower the pipette until the distal end reaches the vicinity of the bottom portion of the long vial 101. In this case, the pipette 211 (311) stops the movement immediately before the distal end contacts the bottom portion of the long vial 101, unlike to the case of the microtube 102. Thus, when aspirating the blood accommodated in the long vial 101, the pipette 211 (311) does not contact the bottom portion of the long vial 101, and thus the long vial 101 is not damaged by the pipette 211 (311). The stepping motor 218 (318) is configured such that the rotation speed fluctuates according to the frequency of the drive pulse.

The detection sections 23 and 33 are configured to perform RBC detection (detection of red blood cells) and PLT detection (detection of platelet) through the sheath flow DC detection method, and perform HGB detection (detection of blood pigment in blood) through the SLS-hemoglobin method. The detection sections 23 and 33 are also configured to perform WBC detection (detection of white blood cells) through the flow cytometry method using a semiconductor laser.

The detection results obtained in the detection sections 23 and 33 are transmitted to the control device 5 as measurement data (measurement result) of the specimen. The measurement data is data that serves as the final analysis result (number of red blood cells, number of platelets, hemoglobin amount, number of white blood cells, and the like) provided to the user.

As shown in FIG. 4, the sample container conveying sections 25 and 35 include, hand portions 251, 351 capable of gripping the long vial 101, open/close portions 252, 352 for opening/closing the hand portions 251, 351 so as to grip the long vial 101, vertical movement portions 253, 353 for linearly moving the hand portions 251, 351 in the vertical direction (direction of arrows Z1 and Z2), and stirring portion 254, 354 for moving the hand portions 251, 351 in a pendulum-form in the vertical direction (direction of arrows Z1 and Z2), respectively. Furthermore, the sample container conveying sections 25 and 35 include sample container transfer sections 255, 355 for substantially horizontally moving the sample container 100 in the directions of the arrows Y1 and Y2, and barcode readers 256, 356, respectively, as shown in FIG. 3.

The hand portion 251 (351) is arranged on the upper side of the conveyance path of a rack 110 conveyed by the specimen conveying device 4. The hand portions 251 and 351 are each configured to move downward (direction of arrow Z2) when the long vial 101 is conveyed to a first provision 43 a and a second provision position 43 b (see FIG. 3), to be hereinafter described, by the specimen conveying device 4, and then to be opened/closed by the open/close portions 252, 352 to grip the long vial 101 accommodated in the rack 110. In this case, the movement portion 255 d (355 d), to be hereinafter described, of the sample container transfer section 255 (355) is accommodated on the back side (side on direction of arrow Y2) than the front surface portion 241 (341) of the unit cover 24 (34), and thus the movement to the lower side of the hand portion 251 (351) is not inhibited.

The hand portion 251 (351) is configured to take out the gripped long vial 101 from the rack 110 by moving to the upper side (direction of arrow Z1), and thereafter, to be moved (e.g., ten rounds) in the pendulum-form by the stirring portion 254 (354). The hand portion 251 (351) thus can stir the blood in the gripped long vial 101. After terminating the stirring, the hand portion 251 (351) moves to the lower side (direction of arrow Z2), and releases the gripping of the long vial 101 by the open/close portion 252 (352). Specifically, the hand portion 251 (351) is configured to set the long vial 101 at a first specimen setting portion 255 a (355 a) moved to the specimen set position 610 (710) (see FIG. 3) by the sample container transfer section 255 (355). The hand portion 251 (351) thus can transfer the long vial 101 from the rack 101 to the first specimen setting portion 255 a (355 a) by moving the long vial 101 in the up and down directions (direction of arrows Z1 and Z2) at substantially the same position in plan view. As shown in FIG. 3, in plan view, the first provision position 43 a and the specimen set position 610 are arranged to overlap, and the second provision position 43 b and the specimen set position 710 are arranged to overlap.

The above operation of taking out the long vial 101 from the rack 110 conveyed by the specimen conveying device 4, and setting the same in the first specimen setting portion 255 a (355 a) is executed by controlling the stepping motor 253 a (353 a) for moving the hand portion 251 (351) up and down, a stepping motor 431 e for driving a first belt 431, and a stepping motor 432 e for driving a second belt 432 (see FIG. 4) by the CPU 51 a to be hereinafter described.

In other words, the CPU 51 a first executes the process of conveying the long vial 101 to the first provision position 43 a (43 b) by the specimen conveying device 4. When the movement portion 255 d (355 d) is not present on the upper side of the first provision position 43 a (43 b), the CPU 51 a executes the process of gripping the long vial 101 by means of the hand portion 251 (351), raising the long vial 101 until the lower end of the long vial 101 is positioned on the upper side than the upper end face of the first specimen setting portion 255 a (355 a), and stirring the long vial 101. The CPU 51 a then executes the process of moving the movement portion 255 d (355 d) until the first specimen setting portion 255 a (355 d) is positioned immediately below the raised long vial 101. The CPU 51 a executes the process of lowering the hand portion 251 (351) and releasing the gripping to set the long vial 101 in the first specimen setting portion 255 a (355 d). The CPU 51 a then executes the process of moving the movement portion 255 d (355 d) until the long vial 101 set in the first specimen setting portion 255 a (355 d) is positioned at the aspiration position 600 (700).

The open/close portion 252 (352) is configured to open/close the hand portion 251 (351) so as to grip the long vial 101 by the power of the air cylinder 252 a (352 a).

The vertical movement portion 253 (353) is configured to move the hand portion 251 (351) in the vertical direction (direction of arrows Z1 and Z2) along the rail 253 b (353 b) by the power of the stepping motor 253 a (353 a).

The stirring portion 254 (354) is configured to move the hand portion 251 (351) in the pendulum-form in the vertical direction (direction of arrows Z1 and Z2) by the power of a stepping motor (not shown).

As shown in FIGS. 8 and 9, sample container transfer sections 255 and 355 include the first specimen setting portions 255 a, 355 a, the second specimen setting portions 255 b, 355 b arranged on the front side (side on direction of arrow Y1) than the first specimen setting portions 255 a, 355 a, the movement portions 255 d, 355 d attached with such two specimen setting portions by way of the adapters 255 c, 355 c, the stepping motors 255 e, 355 e (see FIG. 9), and the annular timing belts 255 f, 355 f (see FIG. 9), respectively.

As shown in FIG. 9, pulleys 255 g and 355 g are attached to the output shaft of the stepping motors 255 e and 355 e, respectively. The timing belts 255 f and 355 f are turnably stretched respectively by the pulleys 255 g, 355 g and the pulleys 255 h, 355 h arranged on the front side (side on direction of arrow Y1) than the stepping motors 255 e, 355 e. Thus, when the stepping motor 255 e (355 e) is rotatably driven, the timing belt 255 f (355 f) is turned between the pulley 255 g (355 g) and the pulley 255 h (355 h). Part of the timing belt 255 f (355 f) is arranged to extend in the front and back direction (direction of arrows Y1 and Y2), and the movement portion 255 d (355 d) is attached to the portion arranged to extend in the front and back directions of the timing belt 255 f (355 f) by an attachment 255 i (355 i) near the back end. The movement portion 255 d (355 d) then can be moved in the front and back directions (direction of arrows Y1 and Y2) with the turning of the timing belt 255 f (355 f).

The first specimen setting portion 255 a (355 a) attached to the movement portion 255 d (355 d) and the second specimen setting portion 255 b (355 b) can be moved to a predetermined position corresponding to the operation of the measurement process by controlling the rotational drive of the stepping motor 255 e (355 e). Specifically, each of specimen setting portions can be arranged at the aspiration positions 600, 700, the specimen set positions 610, 710, the priority specimen set positions 620, 720, and the test tube presence detection positions 630, 730 shown in FIG. 3 by the sample container transfer sections 255, 355. As shown in FIG. 3, each position above is on the movement path of the specimen setting portion in the order of, from the front side (side on direction of arrow Y1) of the blood analyzer 1, the priority specimen set position 620 (720) arranged on the front side than the front surface portion 241 (341) of the unit cover 24 (34), the specimen set position 610 (710) arranged on the back side (side on direction of arrow Y2) than the front surface portion 241 (341), the test tube presence detection position 630 (730), and the aspiration position 600 (700).

In the present embodiment, as shown in FIG. 3, the sample container transfer section 255 (355) is configured to, in plan view, pass the upper side of the conveyance path of the rack 110 and move each specimen setting portion to a predetermined position so that the movement portion 255 d (355 d) is orthogonal to the conveyance path of the rack 110 conveyed by the specimen conveying device 4. Specifically, as shown in FIG. 10, the movement portion 255 d (355 d) is arranged at a position H1 higher than an upper end position H2 of the rack 110 conveyed by the specimen conveying device 4, and is configured to be moved in the front and back directions (direction of arrows Y1 and 2) at substantially the horizontal direction. Each specimen setting portion attached to the movement portion 255 d (355 d) then can be conveyed to the predetermined position while continuing the conveying operation of the rack 110 by the specimen conveying device 4.

The first specimen setting portions 255 a, 355 a have holding holes 255 h, 355 j, respectively, as shown in FIG. 8, wherein the long vial 101 (see FIG. 5) can be held in the holding holes 255 j, 355 j. Cutouts 255 k, 355 k are formed at the side surface on the back side (side on direction of arrow Y2) of the first specimen setting portions 255 a, 355 a so that the rear side (side on direction of arrow Y2) of the holding holes 255 j, 355 j is opened. Thus, the barcode 101 b (see FIG. 5 b) attached to the long vial 101 can be visually recognized from the outer side with the long vial 101 held in the first specimen setting portion 255 a (355 a). The first specimen setting portion 255 a (355 a) is removably attached to the adapter 255 c (355 c), and can be changed with other first specimen setting portion depending on the type of the long vial 101.

The second specimen setting portions 255 b, 355 b have upper holders 255 l, 355 l and lower holders 255 m, 355 m, respectively. The second specimen setting portion 255 b (355 b) holds the upper side of the microtube 102 (see FIG. 6) by the upper holder 255 l (355 l), and holds the lower side of the microtube 102 (see FIG. 6) by the lower holder 255 m (355 m), so that the microtube 102 is held at two locations of different lengths, and thus can be held in a stable state. The upper holders 255 l, 355 l are formed with holding holes 255 n, 355 n, respectively, and separating portions 255 o, 355 o for dividing the upper holders 255 l, 355 l into two in the left and right directions (directions of arrow X1 and X2) are formed at the front and back portions of the holding holes 255 n, 355 n. The portion divided into two in the left and right direction is supported by two supporting portions 255 p, 355 p elastically deformable to the outer side direction, respectively. Thus, if the supporting portion 255 p (355 p) for supporting the portion divided into two in the left and right directions is bent in the outer side direction, the inner diameter of the holding hole 255 n (355 n) can be changed, and as a result, a plurality of types of microtubes 102 having different size can be held.

The lower holders 255 m, 355 m have holding holes 255 q, 355 q at a position corresponding to the position of the holding holes 255 n, 355 n of the upper holders 255 l, 355 l in plan view, and hold the lower side of the microtube 102 with the lower end of the microtube 102 inserted in the holding holes 255 q, 355 q, respectively. Furthermore, the second specimen setting portion 255 b (355 b) is removably attached to the adapter 255 c (355 c), and can be changed with other second specimen setting portion so as to respond to the microtube 102 of the type that cannot be responded with the flexural deformation of the supporting portion 255 p (355 p).

The barcode reader 256 (356) is configured to read the barcode 101 b attached to each long vial 101, as shown in FIG. 5. The barcode reader 256 (356) is also configured to read the barcode 101 while rotating the target long vial 101 in the horizontal direction by a rotating device (not shown) while being held at the first specimen setting portion 255 a (355 a). Even if the barcode 101 b of the long vial 101 is attached to the opposite side with respect to the barcode reader 256 (356), the barcode 101 b can be directed to the barcode reader 256 (356) side by rotating the long vial 101. The barcode 101 b of each long vial 101 is uniquely attached to each specimen, and is used to manage the analysis result of each specimen, and the like. As shown in FIG. 3, the presence detection section 26 (36) is arranged on the movement path of the case that the first specimen setting portion 255 a (355 a) and the second specimen setting portion 255 b (355 b) are moved from the priority specimen set position 620 (720) to the aspiration position 600 (700).

As shown in FIG. 11, the fixing holder 27 (37) is configured to fixedly hold the long vial 101 transferred to the aspiration position 600 (700). As shown in FIG. 12, the fixing holder 27 (37) is configured not to fixedly hold with respect to the microtube 102 transferred to the aspiration position 600 (700). When using the microtube 102, the microtube 102 is stably held using the flexural deformation of the supporting portion 255 p (355 p) of the second specimen setting portion 255 b (355 b), as described above, and thus the fixing holder 27 (37) does not need to be used. The fixing holders 27 and 37 have a pair of sandwiching parts 271, 371, slide rails 272, 372 arranged to extend horizontally in the direction of arrows X1 and X2, and slidable members 273, 373 slidably attached to the slide rails 272, 372, respectively, as shown in FIGS. 11 and 12. Furthermore, the fixing holders 27, 37 have stepping motors 274, 374, annular timing belts 275, 375, a plurality of pulleys 276, 376, and position sensors 277, 377, respectively, as shown in FIG. 9.

As shown in FIGS. 11 to 14, the pair of sandwiching parts 271, 371 has the opposing side surfaces formed to a substantially V-shape in plan view, so that the long vial 101 of different size, outer shape, and the like can be responded. As shown in FIGS. 11 and 12, the pair of sandwiching parts 271 (371) is attached to the slidable member 273 (373) and is also attached to the timing belt 275 (375) by the coupling part 278 (378). Thus, the pair of sandwiching parts 271 (371) are moved in the horizontal direction integral with the slidable member 273 (373) with the turning of the timing belt 275 (375). The annular timing belt 275 (375) is configured to turn while being guided by the plurality of pulleys 276 (376) when the stepping motor 274 (374) is rotationally driven. As shown in FIG. 9, the annular timing belt 275 (375) is turnably stretched so as to be a predetermined shape by the plurality of pulleys 276 (376). Specifically, the timing belt 275 (375) is formed to two upper and lower stages by folding back the portion arranged extending horizontally in the directions of the arrows X1 and X2 by the pulley 276 (376). Thus, when the timing belt 275 (375) is turned, the upper portion and the lower portion of the two upper and lower stages are moved in opposite directions, directions of arrows X1 and X2, with respect to each other.

The coupling part 278 (378) attached to one of the pair of sandwiching parts 271 (371) is fixed at the upper portion of the two upper and lower stages extending horizontally in the directions of the arrows X1 and X2. The coupling part 278 (378) attached to the other of the pair of sandwiching parts 271 (371) is fixed to the lower portion of the two upper and lower stages extending horizontally in the directions of the arrows X1 and X2. Therefore, as shown in FIGS. 13 and 14, the pair of sandwiching parts 271 (371) is moved in the direction that the distance with respect to each other becomes small when the timing belt 275 (375) is turned in the direction of arrow P1, and moved in the direction that the distance with respect to each other becomes large when the timing belt 275 (375) is turned in the direction of arrow P2. Furthermore, the pair of sandwiching parts 271 (371) can be moved while maintaining the center position 0 of the region sandwiched by the pair of sandwiching parts 271 (371) at substantially the same position by being configured as above. Thus, the pair of sandwiching parts 271 (371) is attached to the timing belt 275 (375) by way of the coupling part 278 (378) such that the center position 0 of the region sandwiched by the pair of sandwiching parts 271 (371) is substantially the same position as the lowered position of the pipette 211 (311) lowered in the vertical direction when seen in plan view. The pair of sandwiching parts 271 (371) is also configured to move so as to contact from both sides while maintaining substantially the same distance with respect to the long vial 101 transferred to the aspiration position 600 (700). Therefore, when seen in plan view, the center axis of the long vial 101 fixedly held by the pair of sandwiching parts 271 (371) can be substantially coincided with the lowered position of the pipette 211 (311).

The position sensor 277 (377) has a cutout and is formed to a substantially U-shape. The position sensor 277 (377) is configured to detect the coupling part 278 (378) traversing the cutout. The CPU 51 a of the control device 5, to be hereinafter described, can judge the position of the pair of sandwiching parts 271 (371) based on the detection result of the position sensor 277 (377), and the number of stepping of the stepping motor 274 (374).

The specimen setting portion open/close button 28 (38) is configured to be pushed by the user when performing the measurement of the priority specimen measured in preference to the continuous measurement specimen (specimen to be measured continuously) accommodated in the long vial 101 held at the rack 110.

The priority specimen measurement start button 29 (39) is configured to be pushed by the user. When the user pushes the priority specimen measurement start button 29 (39) after setting the long vial 101 or the microtube 102 accommodating the priority specimen in the first specimen setting portion 255 a (355 a) or the second setting portion 255 b (355 b), the set long vial 101 or the microtube 102 is taken into the measurement unit, and the measurement is started.

As shown in FIGS. 4 and 15, the specimen conveying device 4 includes a pre-analysis rack holder 41 capable of holding a plurality of racks 110 accommodating the long vial 101 for accommodating the specimen before being subjected to analysis, a post-analysis rack holder 42 capable of holding the plurality of racks 110 accommodating the long vial 101 for accommodating the specimen after being subjected to analysis, a rack conveying unit 43 for linearly moving the rack 110 horizontally in the directions of the arrows X1 and X2, a barcode reader 44, a presence detection sensor 45 (see FIG. 4) for detecting the presence of the long vial 101, and a rack feed-out unit 46 for moving the rack 110 into the post-analysis rack holder 42.

The pre-analysis rack holder 41 includes a rack feed-in unit 411, where the rack 110 held by the pre-analysis rack holder 41 is pushed out onto the rack conveying unit 43 one at a time when the rack feed-in unit 411 moves in the direction of arrow Y2. The rack feed-in unit 411 is configured to be driven by a stepping motor (not shown) arranged at the lower side of the pre-analysis rack holder 41. The pre-analysis rack holder 41 has a regulating part 412 (see FIG. 4) in the vicinity of the rack conveying unit 43, and is configured to regulate the movement of the rack 110 so that the rack 110 that has once been pushed out onto the rack conveying unit 43 does not return to the pre-analysis rack holder 41.

The post-analysis rack holder 42 has a regulating part 421 (see FIG. 4) in the vicinity of the rack conveying unit 43, and is configured to regulate the movement of the rack 110 so that the rack 110 that has once been moved into the post-analysis rack holder 42 does not return to the rack conveying unit 43 side.

As shown in FIG. 3, the rack conveying unit 43 is configured to be able to convey the rack 110 such that the specimen is conveyed to the first provision position 43 a for providing the specimen to the first measurement unit 2 and the second provision position 43 b for providing the specimen to the second measurement unit 3. Furthermore, the rack conveying unit 43 is configured to be able to convey the rack 110 such that the specimen is conveyed to a specimen presence check position 43 c for the presence detection sensor 45 to check the presence of the sample container 100 for accommodating the specimen and a read position 43 d for the barcode reader 44 to read the barcode 101 b (see FIG. 5) of the long vial 101 accommodating the specimen.

As shown in FIGS. 4 and 15, the rack conveying unit 43 includes two belts, first belt 431 and second belt 432, which can move independent from each other. The widths b1 and b2 (see FIG. 15) in the directions of the arrows Y1 and Y2 of the first belt 431 and the second belt 432 have a magnitude of smaller than or equal to half of the width B of the directions of the arrows Y1 and Y2 of the rack 110, respectively. Thus, when the rack conveying unit 43 conveys the rack 110, the first belt 431 and the second belt 432 are both arranged in parallel so as not to exceed the width B of the rack 110. As shown in FIGS. 16 and 17, the first belt 431 and the second belt 432 are formed to an annular shape, and are arranged so as to surround the rollers 431 a, 431 b, 431 c, and the rollers 432 a, 432 b, 432 c, respectively. Projecting pieces 431 d, 432 d are formed by twos at the outer peripheral part of the first belt 431 and the second belt 432 so as to have an inner width w1 (see FIG. 16) and w2 (see FIG. 17) slightly (e.g., about 1 mm) larger than the width W in the directions of the arrows X1 and X2 of the rack 110. The first belt 431 is configured to move the rack 110 in the directions of the arrows X1 and X2 by being moved at the outer periphery of the rollers 431 a to 431 c by the stepping motor 431 e (see FIG. 4) with the rack 110 held at the inner side of the projecting piece 431 d. The second belt 432 is configured to move the rack 110 in the directions of the arrows X1 and X2 by being moved at the outer periphery of the rollers 432 a to 432 c by the stepping motor 432 e (see FIG. 4) with the rack 110 held at the inner side of the projecting piece 432 d. The first belt 431 and the second belt 432 are each configured to be able to move the rack 110 independent from each other.

The barcode reader 44 is configured to read the barcode 101 b attached to each long vial 101 shown in FIG. 5, and to read the barcode 110 a attached to the rack 110. The barcode reader 44 is also configured to read the barcode 101 while rotating the target long vial 101 in the horizontal direction by a rotating device (not shown) while being accommodated in the rack 110. Thus, even if the barcode 101 b of the long vial 101 is attached to the opposite side with respect to the barcode reader 44, the barcode 101 b can be directed to the barcode reader 44 side by rotating the long vial 101. The barcode 110 a of the rack 110 is uniquely attached to each rack, and is used to manage the analysis result of the specimen, and the like.

The presence detection sensor 45 is a contact type sensor, and includes a curtain-shaped contact piece 451 (see FIG. 4), a light emitting element (not shown) for emitting light, and a light receiving element (not shown). The presence detection sensor 45 is configured such that the contact piece 451 is bent by contacting a detecting object to be detected, and as a result, the light exited from the light emitting element is reflected by the contact piece 451 and entered to the light receiving element. Therefore, when the long vial 101 to be detected accommodated in the rack 110 passes the lower side of the presence detection sensor 45, the contact piece 451 is bent by the long vial 101, and the presence of the long vial 101 can be detected.

The rack feed-out unit 46 is arranged so as to face the post-analysis rack holder 42 with the rack conveying unit 43 in between, and is configured to move horizontally in the direction of arrow Y1. Thus, when the rack 110 is conveyed to between the post-analysis rack holder 42 and the rack feed-out unit 46, the rack 110 is pushed and moved into the post-analysis rack holder 42 by moving the rack feed-out unit 46 to the post-analysis rack holder 42 side.

As shown in FIGS. 1 to 3 and 18, the control device 5 is configured by a personal computer (PC) and the like, and includes a control unit 51 (see FIG. 18) including CPU, ROM, and RAM, a display unit 52, and an input device 53. The display unit 52 is arranged to display the analysis result and the like obtained by analyzing the data of the digital signal transmitted from the first measurement unit 2 and the second measurement unit 3. As shown in FIG. 19, the display unit 52 is configured to display a priority specimen measurement instruction screen 520 for the user to perform input of a specimen identification number for identifying the specimen, measurement item setting, and the like in the measurement of the priority specimen that needs to be measured in preference to other specimens.

The configuration of the control device 5 will now be described. As shown in FIG. 18, the control device 5 is configured by a computer 500 mainly configured by a control unit 51, a display unit 52, and an input device 53. The control unit 51 is mainly configured by a CPU 51 a, a ROM 51 b, a RAM 51 c, a hard disc 51 d, a read-out device 51 e, an input/output interface 51 f, a communication interface 51 g, and an image output interface 51 h. The CPU 51 a, the ROM 51 b, the RAM 51 c, the hard disc 51 d, the read-out device 51 e, the input/output interface 51 f, the communication interface 51 g, and the image output interface 51 h are connected by a bus 51 i.

The CPU 51 a can execute computer programs stored in the ROM 51 b and the computer programs loaded in the RAM 51 c. The computer 500 serves as the control device 5 when the CPU 51 a executes the application programs 54 a, 54 b and 54 c.

The ROM 51 b is configured by mask ROM, PROM, EPROM, EEPROM, and the like, and is recorded with computer programs to be executed by the CPU 51 a, data used for the same, and the like.

The RAM 51 c is configured by SRAM, DRAM, and the like. The RAM 51 c is used to read out the computer programs recorded on the ROM 51 b and the hard disc 51 d. The RAM 51 c is used as a work region of the CPU 51 a when executing the computer programs.

The hard disc 51 d is installed with various computer programs to be executed by the CPU 51 a such as operating system and application program, as well as data used in executing the computer program. The measurement process (1) program 54 a for the first measurement unit 2, the measurement process (2) program 54 b for the second measurement unit 3, and the sample operation process program 54 c for the specimen conveying device 4 are also installed in the hard disc 51 d. When the CPU 51 a executes such application programs 54 a to 54Zc, the operation of each portion of the first measurement unit 2, the second measurement unit 3, and the specimen conveying device 4 is controlled. The measurement result database 54 d is also installed in the hard disc 51 d.

The read-out device 51 e is configured by flexible disc drive, CD-ROM drive, DVD-ROM drive, and the like, and is able to read out computer programs and data recorded on a portable recording medium 54. The application programs 54 a to 54 c are stored in the portable recording medium 54, wherein the computer 500 reads out the application programs 54 a to 54 c from the portable recording medium 54, and installs the application programs 54 a to 54 c in the hard disc 51 d.

The application programs 54 a to 54 c are not only provided by the portable recording medium 54, but are also provided through communication line (wired or wireless) from external devices communicably connected with the computer 500 through the communication line. For instance, the application programs 54 a to 54 c may be stored in the hard disc of the server computer on Internet, so that the computer 500 can access the server computer to download the application programs 54 a to 54 c and install the same in the hard disc 51 d.

Operating system providing graphical user interface environment such as Windows (registered trademark) manufactured and sold by US Microsoft Co. is installed in the hard disc 51 d. In the following description, the application programs 54 a to 54 c are assumed to operate on the operating system.

The input/output interface 51 f is configured by serial interface such as USB, IEEE1394, RS-232C; parallel interface such as SCSI, IDE, IEEE1284; analog interface such as D/A converter, A/D converter, and the like. The input device 53 is connected to the input/output interface 51 f, so that the user can input data to the computer 500 by using the input device 53.

The communication interface 51 g is, for example, Ethernet (registered trademark) interface. The computer 500 transmits and receives data with the first measurement unit 2, the second measurement unit 3, the specimen conveying device 4, and the host computer 6 by using a predetermined communication protocol by means of the communication interface 51 g.

The image output interface 51 h is connected to the display unit 52 configured by LCD, CRT, or the like, and is configured to output an image signal corresponding to the image data provided from the CPU 51 a to the display unit 52. The display unit 52 displays the image (screen) according to the input image signal.

According to the above configuration, the control unit 51 analyzes the component to be analyzed using the measurement results transmitted from the first measurement unit 2 and the second measurement unit 3, and acquires the analysis result (number of red blood cells, number of platelets, amount of hemoglobin, number of white blood cells, and the like).

As shown in FIG. 5, the rack 110 is formed with ten container accommodating portions 110 b so as to accommodate ten sample containers 100 in a line. Each container accommodating portion 110 b is provided with an opening 110 c such that the barcode 101 b of the accommodated long vial 101 can be visually recognized.

FIG. 20 is a flowchart describing the measurement processing operation by the measurement process program of the blood analyzer according to one embodiment shown in FIG. 1. The measurement processing operation by the measurement process programs 54 a and 54 b of the blood analyzer 1 according to one embodiment will be described with reference to FIGS. 3 and 20. The component to be analyzed is similarly measured in the first measurement unit 2 and the second measurement unit 3, and thus a case of measuring the component to be analyzed by the first measurement unit 2 will be described below as a representative example.

First, in step S1, the specimen is aspirated by the specimen aspiration section 21 from the sample container 100 conveyed to the aspiration position 600 shown in FIG. 3. In step S2, the detection sample is prepared by the sample preparation section 22 from the aspirated specimen, and in step S3, the component to be analyzed is detected by the detection section 23 from the detection sample. In step S4, the measurement data is transmitted from the first measurement unit 2 to the control device 5. Thereafter, in step S5, the component to be analyzed by the control unit 51 is analyzed based on the measurement result transmitted from the first measurement unit 2. The analysis of the specimen is completed and the operation is terminated by step S5.

FIG. 21 is a flowchart describing the operation in the priority specimen measurement of the blood analyzer according to one embodiment shown in FIG. 1. FIGS. 22 to 25 are state diagrams for describing the operation in the priority specimen measurement of the blood analyzer according to one embodiment shown in FIG. 1. The operation in the priority specimen measurement of the blood analyzer 1 according to one embodiment will be described below with reference to FIGS. 1, 2, 19, and 21 to 25. In the present embodiment, the first measurement unit 2 and the second measurement unit 3 can measure the priority specimen independent from each other, and the operations in the priority specimen measurement in the first measurement unit 2 and the second measurement unit 3 are the same. Therefore, the operations in the priority specimen measurement in the first measurement unit 2 will be described herein as a representative example.

First, in step S101 shown in FIG. 21, the CPU 51 a judges whether or not the specimen setting portion open/close button 28 (see FIGS. 1 and 2) is pushed, and repeats the judgment until the button is pushed. When the button is pushed, the movement portion 255 d is moved so as to project out from the front surface portion 241 of the unit cover 24, and the first specimen setting portion 255 a and the second specimen setting portion 255 b are arranged at the priority specimen set position 620 in step S102, as shown in FIG. 22.

In step S103, the priority specimen measurement instruction screen 520 is displayed on the display unit 52, as shown in FIG. 19. In step S104, the user inputs the specimen identification number and sets the measurement items, and thereafter, the CPU 51 a judges whether or not the OK button 520 a displayed on the priority specimen measurement instruction screen 520 is pushed. This judgment is continued until the OK button 520 a is pushed. When the cancel button 520 b is pushed, the priority specimen measurement instruction screen 520 is terminated. When the OK button 520 a of the priority specimen measurement instruction screen 520 is pushed, the CPU 51 a judges whether or not the priority specimen measurement start button 29 (see FIGS. 1 and 2) is pushed in step S105. The user sets the long vial 101 or the microtube 102 accommodating the priority specimen in the first specimen setting portion 255 a or the second specimen setting portion 522 b after pushing the OK button 520 a, and then pushes the priority specimen measurement start button 29. This judgment is repeated if the priority specimen measurement start button 29 is not pushed, and if the button is pushed, the first specimen setting portion 255 a is moved to the test tube presence detection position 630, and the presence of the long vial 101 is detected by the presence detection section 26 in step S106, as shown in FIG. 23. The user sets the microtube 102 in the second specimen setting portion 255 b with the lid of the microtube 102 detached when measuring the priority specimen accommodated in the microtube 102.

In step S107, the CPU 51 a judges whether or not the long vial 101 is set in the first specimen setting portion 255 a based on the detection result, where the first specimen setting portion 255 a is moved to the aspiration position 600 if the long vial 101 is set in step S108, as shown in FIG. 24. Thereafter, the long vial 101 held by the first specimen setting portion 255 a is sandwiched by the pair of sandwiching parts 271 of the fixing holder 27, and the long vial 101 is fixedly held such that the center axis of the long vial 101 is at the lowered position of the pipette 211. The pipette 211 is passed through the sealing lid 101 a, and inserted to the inside of the long vial 101. Specifically, the pipette 211 is lowered by the stepping motor 218, which is rotatably driven at a predetermined rotary torque, passed through the sealing lid 101 a, and thereafter, lowered until the distal end reaches the vicinity of the bottom portion of the long vial 101. After the blood in the long vial 101 is aspirated by the specimen aspiration section 21, the measurement of the priority specimen is performed in step S110.

If the CPU 51 a judges that the long vial 101 is not set in the first specimen setting portion 255 a in step S107, the second specimen setting portion 255 b is moved to the aspiration position 600 in step S109, as shown in FIG. 25. The pipette 211 is inserted to the inside of the microtube 102 held at the second specimen setting portion 255 b, and lowered until the distal end reaches the bottom portion of the microtube 102. After the aspiration operation of the blood by the specimen aspiration section 21 is performed in this state, the process proceeds to step S1 0, and the measurement of the priority specimen is performed. The aspirating amount of blood in step S109 is less than the aspirating amount of blood in step S108.

After the aspiration of blood is completed, the first specimen setting portion 255 a and the second specimen setting portion 255 b are moved to the priority specimen set position 620 by the sample container transfer section 255 in step S111, as shown in FIG. 22. Thereafter, whether or not the priority specimen measurement start button 29 is pushed is judged in step S112. The user removes the long vial 101 or the microtube 102, where the blood has been aspirated, from the first specimen setting portion 255 a or the second specimen setting portion 255 b, then sets the long vial 101 or the microtube 102 accommodating a new priority specimen in the first specimen setting portion 255 a or the second specimen setting portion 255 b, and pushes the priority specimen measurement start button 29 to continuously perform the measurement of the priority specimen. When the user sets the long vial 101 or the microtube 102 accommodating the new priority specimen in the first specimen setting portion 255 a or the second specimen setting portion 255 b, and pushes the priority specimen measurement start button 29, the operation proceeds to step S106, and the measurement of the next priority specimen is continuously performed.

If the priority specimen measurement start button 29 is not pushed, the CPU 51 a judges whether or not the specimen setting portion open/close button 28 is pushed in step S113. The user can terminate the measurement of the priority specimen by pushing the specimen setting portion open/close button 28. If the specimen setting portion open/close button 28 is not pushed, the judgments are repeated until either the priority specimen measurement start button 29 or the specimen setting portion open/close button 28 is pushed. If the specimen setting portion open/close button 28 is pushed, the movement portion 255 d is moved in the direction of arrow Y2 to return the first specimen setting portion 255 a and the second specimen setting portion 255 b inside the unit cover 24 of the first measurement unit 2 in step S114, and the measurement operation of the priority specimen is terminated.

In the present embodiment, a plurality of specimen containers 100 of different types can be responded by arranging the first specimen setting portion 255 a (355 a) and the second specimen setting portion 255 b (355 b) for holding the a plurality of specimen containers 100 of different types (long vial 101 and microtube 102), as described above. With the arrangement of the presence detection section 26 (36) for detecting the presence of the long vial 101 set in the first specimen setting portion 255 a (355 a), and the CPU 51 a for determining in which specimen setting portion, of the first specimen setting portion 255 (355 a) or the second specimen setting portion 255 b (355 b), the sample container 100 is set based on the detection result of the presence detection section 26 (36), and controlling the operation of the specimen aspiration section 21 (31), the aspirating operation corresponding to the specimen setting portion set with the sample container 100 can be automatically carried out by the CPU 51 a based on the detection result of the presence detection section 26 (36) regardless of whether the sample container 100 is set in first specimen setting portion 255 (355 a) or the second specimen setting portion 255 b (355 b), and thus the user does not need to separately perform the operation of manually moving the container holder to set the sample container 100 when setting the sample container 100. Therefore, the burden on the user when setting the sample container 100 can be alleviated while responding to the plurality of specimen containers 100 of different types.

In the present embodiment, the CPU 51 a is configured to control the operation of the sample container transfer section 255 (355) so that the sample container 100 set in either the first specimen setting portion 255 a (355 a) or the second specimen setting portion 255 b (355 b) is moved to the aspiration position 600 (700) based on the detection result of the presence detection section 26 (36), so that the set sample container 100 is moved to the aspiration position 600 (700) based on the detection result of the presence detection section 26 (36) irrespective of which specimen setting portion, the first specimen setting portion 255 a (355 a) or the second specimen setting portion 255 b (355 b), the sample container 100 is set, whereby the user does not need to separately perform the operation of moving the sample container 100 to the aspiration position 600 (700) when setting the sample container 100. Therefore, the burden on the user when setting the sample container 100 can be easily alleviated.

In the present embodiment, the fixing holder 27 (37) is arranged with a pair of sandwiching parts 271 (371) for fixing and holding the long vial 101 set in the first specimen setting portion 255 a (355 a) by sandwiching from the periphery, and the pair of sandwiching parts 271 (371) is configured to move towards the set long vial 101 to sandwich the long vial 101 with the center position 0 of the region to be sandwiched by the pair of sandwiching parts 271 (371) maintained at substantially the same position, whereby the operation of aspirating the specimen can be reliably carried out since the center axis of the set long vial 101 is arranged at the center position 0 of the region to be sandwiched by the pair of sandwiching parts 271 (371) maintained at substantially the same position at the aspiration position 600 (700) even if a long vial 101 of different size is set.

In the present embodiment, the first specimen setting portion 255 a (355 a), and the second specimen setting portion 255 b (355 b) set with the microtube 102 having a smaller size than the long vial 101 set in the first specimen setting portion 255 a (355 a) are arranged, wherein the specimen in the microtube 102 having smaller accommodation capacity than the long vial 101 can be aspirated without waste by configuring the CPU 51 a so as to control the pipette movement portion 212 (312) to move the pipette 211 (311) to a position closer to the bottom of the container in the case that the specimen aspiration section 21 (31) aspirates the specimen from the microtube 102 held in the second specimen setting portion 255 b (355 b) than the case that the aspiration section 21 (31) aspirates the specimen from the long vial 101.

The embodiment disclosed herein is merely illustrative in all aspects and should not be recognized as being restrictive. The scope of the invention is defined by the claims rather than the description of the embodiment as described above, and the meaning equivalent to the claims and all modifications within the scope are encompassed therein.

For instance, the blood analyzer is described as one example of an analyzer in the present embodiment, but the present invention is not limited thereto, and the present invention may be applied to other analyzers as long as the measurement of both the continuous measurement specimen and the priority specimen can be responded.

Furthermore, an analyzer including two measurement units of the first measurement unit and the second measurement unit is described as one example of an analyzer in the present embodiment, but the present invention is not limited thereto, and may be an analyzer including one measurement unit or an analyzer including three or more measurement units.

The CPU, which is one of the control device, for controlling the respective section and portion of both the first measurement unit and the second measurement unit, is described in the present embodiment, but the present invention is not limited thereto, and a plurality of CPUs for controlling the respective section and portion of the first measurement unit and the second measurement unit independently may be provided.

The priority specimen holder including two specimen setting portions, the first specimen setting portion and the second specimen setting portion, has been described as one example of a specimen container setting portion in the present embodiment, but the present invention is not limited thereto, and may be a specimen container setting portion including three or more specimen setting portions.

The analyzer having a configuration of moving the specimen container setting portion from the specimen set position to the aspiration position by the sample container transfer section has been described as one example of an analyzer in the present embodiment, but the present invention is not limited thereto, and may be an analyzer having a configuration of allowing the user to move the specimen container setting portion from the specimen set position to the aspiration position.

The presence detection section for detecting the presence of the long vial has been described as one example of a detection section in the present embodiment, but the present invention is not limited thereto, and may be a detection section for detecting the presence of a microtube, or may be a detection section for detecting the presence of both the long vial and the microtube. Furthermore, two detection sections may be arranged, and the long vial and the microtube may be detected by different detection sections.

The fixing holder for fixing and holding the long vial has been described as one example of a fixing holder in the present embodiment, but the present invention is not limited thereto, and may be a fixing holder for fixing and holding both the long vial and the microtube.

The analyzer equipped with the specimen conveying device has been described as one example of an analyzer in the present embodiment, but the present invention is not limited thereto, and may be an analyzer not equipped with the specimen conveying device.

The hand portion configured to move in the up and down direction (directions of arrows Z1 and Z2) at substantially the same position in plan view has been described as one example of a container transferring mechanism in the present embodiment, but the present invention is not limited thereto, and may be a container transferring mechanism configured to move in a direction tilted with respect to the up and down direction as long as the specimen container can be transferred from the continuous measurement specimen holder to the container holder.

The specimen aspiration section configured to adjust the lowering amount (lowered position) of the pipette depending on the type of specimen container has been described as one example of an aspiration section in the present embodiment, but the present invention is not limited thereto, and may be an aspiration section configured to adjust the aspirating amount of the specimen depending on the type of specimen container. 

1. An analyzer comprising: a specimen container setting portion including a plurality of container holders for holding a plurality of specimen containers of different types; an aspiration section for aspirating the specimen from the specimen container set in the specimen container setting portion; a sensor for detecting the presence of the specimen container set in at least one of the plurality of container holders; and a controller for determining in which of the plurality of container holders the specimen container is set based on the detection result of the sensor, and controlling the operation of the aspiration section.
 2. The analyzer according to claim 1, further comprising a moving assembly for moving the specimen container setting portion to a specimen set position at which the specimen container is set and an aspiration position at which the specimen is aspirated by the aspiration section.
 3. The analyzer according to claim 2, wherein the controller further controls the operation of the moving assembly so that the specimen container set in one of the plurality of container holders is moved to the aspiration position based on the detection result of the sensor.
 4. The analyzer according to claim 2, wherein the sensor is arranged at a position of detecting the specimen container disposed on a path from the specimen set position to the aspiration position.
 5. The analyzer according to claim 2, further comprising an aspiration position holding portion for tightly holding the specimen container set in the container holder at the aspiration position.
 6. The analyzer according to claim 5, wherein the aspiration position holding portion includes a pair of sandwiching parts for holding the specimen container set in the container holder by sandwiching from the periphery; and the pair of sandwiching parts is configured to sandwich the specimen container by moving towards the set specimen container with the center position of the region to be sandwiched by the pair of sandwiching parts maintained at substantially the same position.
 7. The analyzer according to claim 1, wherein the aspiration section includes a pipette and a pipette moving assembly for moving the pipette up and down; and the controller controls the movement of the pipette by the pipette moving assembly based on the detection result of the sensor.
 8. The analyzer according to claim 7, wherein the plurality of container holders include a first container holder, and a second container holder to be set with a specimen container of smaller volume than the specimen container to be set in the first container holder; and the controller controls the pipette moving assembly to move the pipette to a position closer to the bottom of the specimen container in the case that the aspiration section aspirates the specimen from the specimen container held in the second container holder than the case that the aspiration section aspirates the specimen from the specimen container held in the first container holder.
 9. The analyzer according to claim 8, wherein the controller controls the pipette moving assembly so that the pipette reaches the bottom of the specimen container when the aspiration section aspirates the specimen from the specimen container held in the second container holder.
 10. The analyzer according to claim 1, wherein the plurality of container holders include a first container holder, and a second container holder to be set with a specimen container of smaller volume than the specimen container to be set in the first container holder; and the second container holder is arranged on the front side of the analyzer than the first container holder.
 11. The analyzer according to claim 1, wherein the controller controls an aspirating amount of the specimen by the aspiration section based on the detection result of the sensor.
 12. The analyzer according to claim 1, wherein the specimen container setting portion includes two container holders; the sensor detects the presence of the specimen container set in either one of the two container holders; and the controller determines in which of the two container holders the specimen container is set based on the presence of the specimen container, and controls the operation of the aspiration section.
 13. The analyzer according to claim 1, further comprising: a continuous measurement specimen holder configured to hold a plurality of specimen containers accommodating a continuous measurement specimen to be continuously measured; and a container transferring assembly for transferring the specimen container accommodating the continuous measurement specimen from the continuous measurement specimen holder to the container holder; wherein the aspiration section is configured to aspirate the continuous measurement specimen.
 14. An analyzer comprising: a specimen container setting portion including a plurality of container holders for holding a plurality of specimen containers of different types; an aspiration section for aspirating the specimen from the specimen container set in the specimen container setting portion; a moving assembly for moving the specimen container setting portion to a specimen set position at which the specimen container is set and an aspiration position at which the specimen is aspirated by the aspiration section; a sensor for detecting the presence of the specimen container set in at least one of the plurality of container holders; and a controller for controlling the operation of the moving assembly so that the specimen container set in one of the plurality of container holders is moved to the aspiration position based on the detection result of the sensor.
 15. The analyzer according to claim 14, wherein the specimen container setting portion includes two container holders; the sensor detects the presence of the specimen container set in either one of the two container holders; and the controller determines in which of the two container holders the specimen container is set based on the presence of the specimen container, and controls the operation of the moving assembly.
 16. A method for aspirating a specimen comprising: receiving a specimen container in one of a plurality of container holders for holding a plurality of specimen containers of different types; moving a predetermined container holder of the plurality of container holders to a detection position by a sensor for detecting the presence of the specimen container; detecting the presence of the specimen container by the sensor; determining a movement distance of the container holder the received specimen container moves to an aspiration position of the specimen by an aspiration section based on the detection result of the sensor; moving the container holder according to the determined movement distance; and aspirating the specimen from the specimen container by the aspiration section.
 17. The method for aspirating the specimen according to claim 16, wherein the aspirating step includes inserting a pipette into the specimen container; and the distance between the distal end of the pipette and the bottom of the specimen container when the pipette is inserted differs depending on the detection result of the sensor.
 18. The method for aspirating the specimen according to claim 17, wherein the plurality of container holders include a first container holder, and a second container holder to be set with a specimen container of smaller volume than the specimen container to be set in the first container holder; and the distance between the distal end of the pipette and the bottom of the specimen container is larger in the case that the specimen container is set in the first container holder than the case that the specimen container is set in the second container holder.
 19. The method for aspirating the specimen according to claim 18, wherein the distance between the distal end of the pipette and the bottom of the specimen container is zero when the specimen container is set in the second container holder.
 20. The method for aspirating the specimen according to claim 16, wherein an aspirating amount of the specimen in the aspirating step differs depending on the detection result of the sensor. 